Indian Journal of Anaesthesia  
About us | Editorial board | Search | Ahead of print | Current Issue | Past Issues | Instructions
Home | Login  | Users Online: 870  Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size    


CASE REPORT
Year : 2008  |  Volume : 52  |  Issue : 2  |  Page : 208

Dapsone Induced Methaemoglobinemia: Early Intraoperative Detection by Pulse Oximeter Desaturation


Department of Anesthesiology and Critical care, Sheri-Kashmir Institute of medical sciences, Soura, Srinagar, J&K, India

Correspondence Address:
Mahmood Rafiq
Department of Anesthesiology and Critical care, Sheri-Kashmir Institute of medical sciences, Soura, Srinagar, J&K
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Several drugs cause methaemoglobinemia which can lead to pulse oximeter desaturation and hypoxemia.Children with immune thrombocytopenic purpura are being treated with dapsone which is known to cause methaemoglobinemia and many of these can be planned for elective splenectomy. Preoperative knowledge of drug intake and their adverse effects is essential so is the early detection of the cause of intraoperative hypoxemia and the remedial measures taken. We present a child on dapsone therapy for treatment of immune thrombocytopenic purpura planned for elective splenec­tomy developed intraoperative pulseoximeter desaturation. The cause of desaturation was identified as methaemoglobinemia caused by dapsone therapy. Case signifies the importance of knowledge of any preoperative drug intake and its anaesthetic implications. Also patients on dapsone therapy especially children should be monitored for methaemoglobin levels. Since children with immune thrombocy­topenic purpura are being treated with dapsone these days and many of these patients would be planned for splenectomy, monitoring of preoperative methaemoglobin levels and methaemoglobinemia as a cause of intraoperative pulse oximeter desaturation should be kept in mind.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1517    
    Printed55    
    Emailed0    
    PDF Downloaded213    
    Comments [Add]    

Recommend this journal