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CASE REPORT
Year : 2008  |  Volume : 52  |  Issue : 4  |  Page : 462

Intraoperative Anaphylaxis to Inj Ceftriaxone: Here We Go Again


1 Senior Resident, Department of anesthesiology, Intensive Care and perioperative medicine, Maulana Azad Medical College & associated Lok Nayak Hospital, New Delhi, 110034, India
2 Professor, Department of anesthesiology, Intensive Care and perioperative medicine, Maulana Azad Medical College & associated Lok Nayak Hospital, New Delhi, 110034, India

Correspondence Address:
Amit G Bhagwat
NU 17 A Pitam pura, New Delhi 110034, INDIA
India
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Source of Support: None, Conflict of Interest: None


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Anaphylactic reactions to intraoperative antibiotics are rare events and reactions after a negative intradermal skin testing are even rarer. We are reporting a case of grade V anaphylactic reaction to ceftriaxone, which occurred inspite of a negative skin testing preoperatively. Despite of the treatment along the established guidelines, patient suffered hypoxic brain damage ultimately having a fatal outcome 7 days later. This case highlights the limits of the screening test done preoperatively for antibiotic sensitivity and also the difficulty in resuscitating anaphylactic reac­tions when patient is on B blocker and under spinal anaesthesia.


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