Indian Journal of Anaesthesia  
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Year : 2013  |  Volume : 57  |  Issue : 3  |  Page : 282-284

Kounis syndrome resulting from anaphylaxis to diclofenac

1 Department of Anaesthesia, Sushruta Trauma Centre, Civil Lines, New Delhi, India
2 Department of Anaesthesia, St. Stephen's Hospital, Lucknow, Uttar Pradesh, India
3 Department of Cardiothoracic Anaesthesia, Command Hospital (CC), Lucknow, Uttar Pradesh, India

Correspondence Address:
Akhilesh Kumar Tiwari
Opposite SAI Stadium, Post Sarojini Nagar, Kanpur Road, Lucknow 226008, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5049.115614

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"Kounis syndrome" refers to acute coronary syndromes of varying degree (myocardial ischaemia to infarction) induced by mast cell activation as a result of allergic and anaphylactic reactions. ST-segment elevated myocardial infarction is a rare complication that can occur even in patients with normal coronary arteries due to anaphylactic reactions. We present a case that developed acute myocardial infarction following a diclofenac sodium-induced anaphylaxis. The patient did not have any previous coronary artery disease, but there was a temporal relationship with development of the anaphylactic reaction due to diclofenac sodium and the cardiac event. The patient was managed conservatively and the recovery was uneventful.

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