Indian Journal of Anaesthesia  
About us | Editorial board | Search | Ahead of print | Current Issue | Past Issues | Instructions
Home | Login  | Users Online: 596  Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size    


ORIGINAL ARTICLE
Year : 2018  |  Volume : 62  |  Issue : 7  |  Page : 509-515

Effect of epidural levobupivacaine with or without dexamethasone soaked in gelfoam for postoperative analgesia after lumbar laminectomy: A double blind, randomised, controlled trial


1 Department of Anaesthesia and Intensive Care, Dr. S.N. Medical College, Jodhpur, Rajasthan, India
2 Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India
3 Department of Orthopaedics, Dr. S.N. Medical College, Jodhpur, Rajasthan, India
4 Department of Neurosurgery, Dr. S.N. Medical College, Jodhpur, Rajasthan, India

Correspondence Address:
Dr. Manoj Kamal
Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan - 342 005
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ija.IJA_128_18

Rights and Permissions

Background and Aims: Postoperative pain results in prolonged hospital stay and delayed return to normal activity. This study was conducted with the aim of evaluating the analgesic efficacy of gelfoam soaked in levobupivacaine with or without dexamethasone placed in the epidural space in patients undergoing lumbar laminectomy. Methods: Ninety adult patients were randomised into three groups. Gelfoam was soaked in 12 mL of 0.9% sodium chloride in Group P, 10 mL of 0.25% levobupivacaine + 2 mL of 0.9% sodium chloride in Group L, and 10 mL of 0.25% levobupivacaine + 2 mL of dexamethasone in group LD. The primary outcome was time to first request for rescue analgesia. Total 24-h tramadol consumption, and postoperative visual analog scale (VAS) scores were recorded. Chi-square test and analysis of variance test were used, and P < 0.05 was considered significant. Results: 75 patients completed the study. Time to first rescue analgesia was longer in group LD [10.11 ± 3.10 h] compared with group L [6.48 ± 2.36 h] and group P [1.76 ± 1.13 h]. Total 24-h tramadol consumption was lower in group LD (88 ± 66.58 mg) and group L (120 ± 70.7 mg) compared with group P (280 ± 64.5 mg). Postoperative VAS scores were lower in group LD and group L compared with group P, both at rest and on movement. Conclusion: Epidural gelfoam soaked in levobupivacaine and dexamethasone prolongs the duration of analgesia and decreases rescue analgesic consumption and VAS score postoperatively, in patients undergoing lumbar laminectomy.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed637    
    Printed7    
    Emailed0    
    PDF Downloaded267    
    Comments [Add]    

Recommend this journal