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REVIEW ARTICLE
Year : 2008  |  Volume : 52  |  Issue : 1  |  Page : 23

Intensive Insulin Therapy for Critically III Patients: Is It the Necessary Standard of Care?


1 Consultant Department of Anesthesiology, Perioperative Medicine & Pain, Apollo Gleneagles Hospitals, Kolkata., India
2 Consultant in Intensive Care, Directorate of Intensive Care, Royal Liverpool University Hospital, Liverpool., United Kingdom
3 Senior Resident, Department of Anaesthesiology, All India Institute of Medical Sciences, New Delhi., India

Correspondence Address:
Saikat Sengupta
Department of Anesthesiology, Perioperative Medicine & Pain, Apollo Gleneagles Hospitals, 58 Canal Circular Road Kolkata 700054
India
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Source of Support: None, Conflict of Interest: None


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Critically ill patients who require prolonged intensive care support are at high risk of developing multiple organ failure and death. Hyperglycaemia and resistance to insulin are closely associated with major illness or major surgery. This is true irrespective of whether patients are diabetic or not. It has been shown that tight glycaemic control using exogenous intensive insulin therapy improves outcome in critically ill patients. We review the pathophysiology of hyperglycaemia and examine the clinical and economic benefits of such therapy.


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