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CLINICAL INVESTIGATION
Year : 2009  |  Volume : 53  |  Issue : 4  |  Page : 450-454

Caudal Clonidine in Day-Care Paediatric Surgery


1 Consultant, Deptt of Anaesthesiology, Pain and Perioperative medicine, Sir Gangaram Hospital, New Delhi, India
2 Asso. Consultant, Deptt of Anaesthesiology, Pain and Perioperative medicine, Sir Gangaram Hospital, New Delhi, India
3 Senior consultant and Chairperson, Deptt of Anaesthesiology, Pain and Perioperative medicine, Sir Gangaram Hospital, New Delhi, India

Correspondence Address:
Archna Koul
Deptt ofAnaesthesiology, Sir Gangaram Hospital, OldRajinderNagar, New Delhi - 110060
India
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Source of Support: None, Conflict of Interest: None


PMID: 20640207

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We evaluated the analgesic efficacy, hemodynamic and respiratory safety of Clonidine when added to bupivacaine for caudal block. Forty children undergoing inguinal hernia repair were randomly given caudal injection with 0.75 ml.kg -1 of bupivacaine (0.25%) and clonidine 2 µg.kg -1 in Group C or 0.75 ml.kg -1 of bupivacaine (0.25%) alone in Group B after induction of anaesthesia. Postoperatively duration of analgesia, OPS score (observational pain / dis­comfort scale), Sedation score, heart rate and blood pressure were recorded. Duration of analgesia was significantly longer (p< 0.001) in Group C (10.25 hours) as compared to 4.55 hours in Group B. Bradycardia, hypotension and sedation were not observed in Group C. The addition of Clonidine in caudal blocks prolongs postoperativepain relief in children and is safe alternative to bupivacaine alone in paediatric daycare surgeries.


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