| CLINICAL INVESTIGATION |
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| Year : 2009 | Volume
: 53
| Issue : 4 | Page : 450-454 |
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Caudal Clonidine in Day-Care Paediatric Surgery
Archna Koul1, Deepanjali Pant2, Jayshree Sood3
1 Consultant, Deptt of Anaesthesiology, Pain and Perioperative medicine, Sir Gangaram Hospital, New Delhi, India
2 Asso. Consultant, Deptt of Anaesthesiology, Pain and Perioperative medicine, Sir Gangaram Hospital, New Delhi, India
3 Senior consultant and Chairperson, Deptt of Anaesthesiology, Pain and Perioperative medicine, Sir Gangaram Hospital, New Delhi, India
Correspondence Address:
Archna Koul
Deptt ofAnaesthesiology, Sir Gangaram Hospital, OldRajinderNagar, New Delhi - 110060
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 20640207 
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We evaluated the analgesic efficacy, hemodynamic and respiratory safety of Clonidine when added to bupivacaine for caudal block. Forty children undergoing inguinal hernia repair were randomly given caudal injection with 0.75 ml.kg -1 of bupivacaine (0.25%) and clonidine 2 µg.kg -1 in Group C or 0.75 ml.kg -1 of bupivacaine (0.25%) alone in Group B after induction of anaesthesia. Postoperatively duration of analgesia, OPS score (observational pain / discomfort scale), Sedation score, heart rate and blood pressure were recorded. Duration of analgesia was significantly longer (p< 0.001) in Group C (10.25 hours) as compared to 4.55 hours in Group B. Bradycardia, hypotension and sedation were not observed in Group C. The addition of Clonidine in caudal blocks prolongs postoperativepain relief in children and is safe alternative to bupivacaine alone in paediatric daycare surgeries. |
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