Indian Journal of Anaesthesia

CLINICAL INVESTIGATION
Year
: 2010  |  Volume : 54  |  Issue : 2  |  Page : 132--136

Efficacy of intravenous lidocaine in prevention of post extubation laryngospasm in children undergoing cleft palate surgeries


CS Sanikop1, Sonal Bhat2 
1 Department of Anaesthesiology, J.N. Medical College and K.L.E.S.H. and M.R.C, Belgaum - 590 010, Karnataka, India
2 J.N. Medical College and K.L.E.S.H and MRC, Belgaum - 590 010, Karnataka, India

Correspondence Address:
Sonal Bhat
J.N. Medical College and K.L.E.S.H and MRC, Belgaum - 590 010, Karnataka
India

A one-year randomized placebo-controlled trial was conducted to study the effectiveness of intravenous lidocaine in the prevention of post extubation laryngospasm in children, following cleft palate surgeries. Children of age three months to six years were randomly assigned into two groups. Group P placebo (saline) and Group L (Lidocaine), 1.5 mg/kg. A sample size of 74 with n = 37 in each group was selected. The anaesthetic procedure was standardized. At the end of the procedure, three minutes after reversal, the study drug, that is, intravenous lidocaine (1.5 mg/kg) or placebo (saline) was administered and two minutes later the child was extubated. Following extubation for 10 minutes, the haemodynamic parameters, that is, pulse, blood pressure, oxygen saturation, severity of coughing, and laryngospasm were noted. The total reduction of laryngospasm and coughing was 29.9% and 18.92% with IV lidocaine. Significant alterations in haemodynamics and oxygen saturation were noted for 10 minutes, following extubation. Hence, intravenous lidocaine 1.5 mg/kg was effective in the prevention of post extubation laryngospasm in children undergoing cleft palate surgeries.


How to cite this article:
Sanikop C S, Bhat S. Efficacy of intravenous lidocaine in prevention of post extubation laryngospasm in children undergoing cleft palate surgeries.Indian J Anaesth 2010;54:132-136


How to cite this URL:
Sanikop C S, Bhat S. Efficacy of intravenous lidocaine in prevention of post extubation laryngospasm in children undergoing cleft palate surgeries. Indian J Anaesth [serial online] 2010 [cited 2021 Jan 16 ];54:132-136
Available from: https://www.ijaweb.org/article.asp?issn=0019-5049;year=2010;volume=54;issue=2;spage=132;epage=136;aulast=Sanikop;type=0