Figure 4 :Analysis of flinching behaviour in Phase II (15-60 min): Co-administration of L-CCBs + morphine reduced the number of flinches in comparison to morphine alone. However, only nimodipine + morphine showed significant decrease of flinches with reference to the morphine treated group (*). Administration of L-CCBs alone led to significant increase in the flinching behaviour in comparison to the corresponding L-CCB + morphine treated group (”). Values are shown as mean } S.E.M. Statistical evaluation was done by ANOVA and Studentfs t-test (for morphine + nimodipine group in comparison to morphine group). Significance was set at P<0.05.